QRP Research MOTS-c 40mg
MOTS-c (Mitochondrial Open Reading Frame of the 12S rRNA-c) is a naturally occurring 16-amino-acid mitochondrial-derived peptide (MDP) that has attracted significant scientific interest for its role in mitochondrial signalling, cellular metabolism and metabolic homeostasis.
Unlike conventional peptides encoded by nuclear DNA, MOTS-c originates from a short open reading frame within mitochondrial DNA, making it particularly interesting in research examining communication between mitochondria and the rest of the cell.
Experimental studies have identified AMP-activated protein kinase (AMPK) as an important pathway associated with MOTS-c activity. Research has also investigated interactions involving the folate-methionine cycle, AICAR production, glucose metabolism and cellular energy regulation.
Under conditions of metabolic stress, MOTS-c has also been investigated for its ability to participate in mitochondrial-to-nuclear signalling, including translocation to the nucleus and regulation of stress-responsive gene expression.
QRP Research MOTS-c 40mg is supplied as a lyophilised research peptide intended exclusively for controlled laboratory, analytical and scientific investigation.
Key Research Areas
MOTS-c has been investigated experimentally in relation to:
Mitochondrial signalling and communication
AMPK signalling pathways
Cellular energy metabolism
Glucose metabolism
Insulin-related metabolic signalling
Folate-AICAR-AMPK pathways
Mitochondrial-to-nuclear communication
Cellular stress-response mechanisms
Metabolic homeostasis
Skeletal muscle metabolism
Lipid and fatty-acid metabolism
Age-associated metabolic mechanisms
Mitochondrial function and cellular adaptation
A particularly interesting characteristic of MOTS-c is its role as a mitochondrial-derived signalling peptide, providing researchers with a model for investigating how mitochondrial genetic information can influence cellular and nuclear responses.
Experimental research has associated MOTS-c with AMPK activation and alterations in cellular metabolic pathways, while additional studies continue to investigate its broader role in stress adaptation, mitochondrial biology and age-associated metabolic processes.
Research findings involving MOTS-c should not be interpreted as evidence of established therapeutic, anti-ageing, weight-loss, performance-enhancing or other clinical effects in humans.
Product Specification
Compound: MOTS-c
Full Name: Mitochondrial Open Reading Frame of the 12S rRNA-c
Compound Type: Mitochondrial-Derived Peptide (MDP)
Peptide Length: 16 amino acids
Primary Research Pathway: AMPK / Cellular Metabolic Signalling
Form: Lyophilised peptide
Quantity: 40mg per vial
Brand: QRP Research
Application: Laboratory and scientific research
Why QRP Research?
QRP Research supplies specialist research materials with an emphasis on quality, consistency and traceability. Products are securely packaged and clearly identified for their intended laboratory application.
Storage
Store in a cool, dry and dark environment, protected from excessive heat, direct light and moisture.
Appropriate laboratory storage procedures should be followed to preserve the stability and integrity of the research material.
Research Use Notice
FOR RESEARCH USE ONLY.
This product is supplied exclusively for laboratory, analytical and scientific research.
NOT for human consumption or administration.
NOT for animal consumption or administration.
NOT a medicine, food supplement or cosmetic product.
NOT intended to diagnose, treat, cure or prevent any disease.
No human dosing or administration instructions are provided.
Intended to be handled only by appropriately qualified researchers or laboratory professionals.
QRP Research MOTS-c 40mg is supplied strictly as a research material for non-clinical laboratory investigation.